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Article Summary on “THE GENE EDITOR” by Jennifer Doudna

Jennifer Doudna studied biochemistry at the Pomona College in California. After graduation, she joined Jack Szostak who was a potential Nobel laureate. Jack was doing research RNA, and he emphasized that the RNA was the major source of life since the RNA molecules had the ability to amass genetic information and catalyze the chemical reactions. It is notable that Dr. Doudna was awarded the doctoral degree in engineering after she effectively engineered a catalytic RNA that replicated, an aspect that added more evidence to her Gene theories. However, her capability to envision the catalytic RNA limited her works. She successfully carried out an experiment on the atomic structure of the RNA utilizing the X-ray diffraction, despite the fact that she lacked prescribed preparation on the procedure.

In her entire career, Dr Doudna has focused on the structural and biochemical studies of RNA. In the year 2005, Dr. Doudna associated with Jillian Banfield to carry out an experiment on the DNA sequencing of the microbes in the highly acidic mines. It was noted that the genomes of diverse microbes were unusually repeating sequences referred to have “clustered interspaced short palindromic replications.” The scientists managed to establish the sequences, which conveyed the bacterial immune system. It was noted that in the recurring sequences there were stretches of DNA that were derived from the viruses, which affected most bacteria. Dr. Doudna focused on figuring out how the extension of DNA allowed the bacteria to recognize and annihilate the slicing of the genetic materials. The scientists concluded that the cellular defense system would be utilized in the expurgation of genomes rather than just destroying the viruses. Dr. Doudna stated that a sequence of guide RNA could be made to attach a practical spot on a genome and the Cas9 protein divided a DNA on the spot. After the division, it is notable that the DNA would be deleted or replicated.

In conclusion, we note that Dr. Doudna has contributed highly on the DNA research and many scientists have utilized her Crisp-Cas9 theories to create inheritable DNA changes on the embryos. It is evident that there have been genetically modified monkeys that have been produced in China through the Crisp-Cas9 theories.

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